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Looking for good country homes. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of ivermectin topical lotion in children.
However, use is not recommended in infants younger than 6 months of age. Appropriate studies have not been performed on the relationship of age to the effects of ivermectin topical cream in the pediatric population.
Safety and efficacy have not been established. Pregnancy Category C: Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.
Breastfeeding: There are no adequate studies in women for determining infant risk when using this medication during breastfeeding.
Ivermectin is excreted into human milk in low concentrations. The manufacturer recommends that treatment during nursing only occur if the risk of delayed treatment to the mother outweighs the possible risk to the infant.
Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Allergic and inflammatory reactions the Mazzotti reaction may occur with ivermectin, probably due to the death of the microfilariae.
Patients treated with ivermectin therapy for onchocerciasis may experience these reactions in addition to clinical adverse reactions possibly, probably, or definitely related to the therapy itself.
The treatment of severe Mazzotti reactions has not been subjected to controlled clinical studies. After treatment with microfilaricidal medications, patients with hyperreactive onchodermatitis sowda may be more likely than others to experience severe adverse reactions, especially edema and aggravation of onchodermatitis.
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This syndrome has been seen very rarely following the use of ivermectin therapy. Pretreatment assessment for loiasis and careful posttreatment follow-up should be implemented in all patients considered for treatment with ivermectin for any reason and who had exposure to Loa loa endemic areas of West and Central Africa.
The patient should be advised of the need for repeated stool examinations to document clearance of infection with Strongyloides stercoralis.
The patient should be advised that treatment with ivermectin does not kill the adult Onchocerca parasites, and therefore repeated follow-up and retreatment is usually necessary.
In immunocompromised including HIV-infected patients being treated for intestinal strongyloidiasis, repeated courses of therapy may be necessary.
Adequate and well-controlled clinical trials have not been conducted in such patients to determine the optimal dosing regimen.
Several treatments, i. Control of extraintestinal strongyloidiasis in these patients is difficult, and suppressive therapy, i. Ivermectin is extensively metabolized in the liver and should be used cautiously in patients with hepatic disease.
Dosage adjustments may be needed, although specific recommendations are not currently available. The manufacturer does not recommend that ivermectin treatment be excluded in patients with liver disease.
Clinical trials of ivermectin did not include sufficient numbers of patients aged 65 and over to determine whether they respond differently from younger patients.
Other reported clinical experience has not identified differences in responses between elderly and younger patients.
In general, treatment of elderly patients should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.
Safety and effectiveness in pediatric patients weighing less than 15 kg have not been determined.
A recent pharmacokinetics study reports that following a high-fat meal absorption was significantly higher about 2. Ivermectin is usually taken as a single dose.
Tell your doctor if you do not take your medication. Other side effects not listed may also occur in some patients.
If you notice any other effects, check with your healthcare professional. The dose of Ivermectin Topical Application will be different for different patients.
The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of Ivermectin Topical Application that you take depends on the strength of the medicine.
Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
It states that if you don't like the product for any reason you can return the bottle within 90 days of your purchase date for a full refund of the bottle price.
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